abstract：BACKGROUND:Atherosclerosis is widely accepted as a chronic inflammatory disease. Research paid much attention to sensitive specific serum biomarkers for vulnerable plaques. The markers not only serve as diagnostic tools for the identification of patients with acute coronary syndrome (ACS), but also help us to identify ...

journal_title：Clinical cardiology

authors： Tan J,Hua Q,Gao J,Fan ZX

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:In this study, we evaluated the feasibility and clinical usefulness of TS(E-E(') ), the time interval between the onsets of early diastolic mitral inflow velocity (E) and mitral annular velocity (E'), obtained by simultaneously tracing E and E', in terms of evaluating diastolic function. METHODS:By the dias...

journal_title：Clinical cardiology

authors： Choi JO,Park SW,Shin DH,Han H,Cho S,Kim JH,Song YB,Lee SC

更新日期：2008-08-01 00:00:00

abstract：:Three randomized, clinical trials of the drug ranolazine relate to patients with symptomatic myocardial ischemia. A fourth randomized, controlled, clinical trial compares optimal medical therapy with percutaneous coronary intervention (PCI) plus medical therapy. ...

journal_title：Clinical cardiology

authors： Conti CR

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Small heart syndrome has previously been reported as neurocirculatory asthenia, associated with a small heart shadow on a chest roentgenogram. This is characterized as weakness or fatigue even after ordinary exertion, palpitation, dyspnea, and fainting, resembling patients with chronic fatigue syndrome (CFS)...

journal_title：Clinical cardiology

authors： Miwa K,Fujita M

更新日期：2008-07-01 00:00:00

abstract：:The normal human aorta is not a stiff tube but is characterized by elastic properties with a buffering Windkessel function. Aortic stiffening may cause an increase in aortic pulse pressure, left ventricular load, and ultimately left ventricular hypertrophy. This, together with the decreased diastolic transmyocardial p...

journal_title：Clinical cardiology

authors： Nemes A,Geleijnse ML,Forster T,Soliman OI,Ten Cate FJ,Csanády M

更新日期：2008-07-01 00:00:00

abstract：:As I advanced through medical school at Johns Hopkins, and throughout my subsequent training, I was constantly reminded of the contributions made to medicine by our predecessors. Many of whom were at Johns Hopkins, but many were not. As I continue active involvement in the education of medical students and physicians,...

journal_title：Clinical cardiology

authors： Conti CR

更新日期：2008-04-01 00:00:00

abstract：:Despite the proven benefits of using antiplatelet therapy in patients undergoing percutaneous coronary intervention (PCI), a number of key questions remain to be answered. In recent years, clopidogrel dosing strategies among such patients have evolved considerably, with newer approaches involving loading doses prior t...

journal_title：Clinical cardiology

authors： Braunwald E,Angiolillo D,Bates E,Berger PB,Bhatt D,Cannon CP,Furman MI,Gurbel P,Michelson AD,Peterson E,Wiviott S

更新日期：2008-03-01 00:00:00

abstract：:Antiarrhythmic drugs are an essential tool in the management of atrial fibrillation (AF). Although we are already on the threshold of a large expansion in the use of ablation therapies, these will not, however, be appropriate for all patients, and pharmacological therapies will continue to have an important place in t...

journal_title：Clinical cardiology

authors： Savelieva I,Camm J

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Evaluation of chest pain accounts for millions of costly Emergency Department (ED) visits and hospital admissions annually. Of these, approximately 10-20% are myocardial infarctions (MI). HYPOTHESIS:Patients with chest pain whose initial electrocardiogram (ECG) is normal do not require hospital admission fo...

journal_title：Clinical cardiology

authors： Challa PK,Smith KM,Conti CR

更新日期：2007-11-01 00:00:00

abstract：:In-coordinate mitral annulus movement might participate in the pathogenesis of functional mitral regurgitation. We evaluated a relationship between indices of mitral annulus systolic asynchrony and mitral regurgitation in patients after myocardial infarction in order to determine independent determinants of effective ...

journal_title：Clinical cardiology

authors： Szymanski P,Klisiewicz A,Hoffman P

更新日期：2007-10-01 00:00:00

abstract：:The clinical impact of increasing levels of blood loss has been shown to increase morbidity and mortality after percutaneous coronary intervention (PCI). The impact of red blood cell (RBC) transfusion for severe bleeding is unknown. We systematically collected baseline and 8-h postprocedure hematocrit (HCT) values on ...

journal_title：Clinical cardiology

authors： Kim P,Dixon S,Eisenbrey AB,O'Malley B,Boura J,O'Neill W

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Cardiac troponin I (cTnI), N-terminal pro-B-type natriuretic peptide (NT-proBNP) and high-sensitivity C-reactive protein (hsCRP) each predict adverse cardiac events in chronic heart failure (CHF). However, little is known about the utility of these novel biomarkers of CHF in combination. HYPOTHESIS:: We hyp...

journal_title：Clinical cardiology

authors： Yin WH,Chen JW,Feng AN,Lin SJ,Young S

更新日期：2007-08-01 00:00:00

abstract：:Transient left ventricular (LV) apical ballooning and normal epicardial coronary arteries are the hallmarks of Takotsubo cardiomyopathy. The syndrome is often triggered by emotional or physiologic stress, and its pathogenesis is poorly understood. Current proposals focus on elevated cathecolamines in association with ...

journal_title：Clinical cardiology

authors： Novak G,Kross K,Follmer K,Brofferio A,Shirani J

更新日期：2007-07-01 00:00:00

abstract：:The prediction of significant left main or diffuse three-vessel coronary artery disease is crucial in patients presenting with an acute coronary syndrome. ST-segment elevation in aVR has been reported to be associated with left main coronary artery obstruction or severe diffuse coronary artery disease in acute coronar...

journal_title：Clinical cardiology

authors： Habibzadeh MR,Ewy GA

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Most information concerning hypertrophic cardiomyopathy has been derived from western countries and Japan. HYPOTHESIS:Patients with hypertrophic cardiomyopathy in Taiwan may have a distinct morphology and clinical picture. METHODS:Information from 163 consecutive patients with hypertrophic cardiomyopathy a...

journal_title：Clinical cardiology

authors： Lee CH,Liu PY,Lin LJ,Chen JH,Tsai LM

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:The objective of this study was to estimate the prevalence of prehypertension and hypertension in the rural adults of Liaoning province of China. METHODS:The study was conducted in 2004-2006, using a multistage cluster sampling method to select a representative sample. A total of 45925 adults, 35 years or o...

journal_title：Clinical cardiology

authors： Sun Z,Zheng L,Wei Y,Li J,Zhang X,Zhang X,Liu S,Xu C,Li J,Zhao F,Dong G,Hu D,Sun Y

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:In animal models, pretreatment with angiotensin-converting enzyme inhibitor (ACEI) can reduce no-reflow. In the present study, we investigated whether pretreatment with ACEI may prevent no-reflow in patients who underwent primary coronary intervention for AMI. METHOD AND RESULTS:A total of 259 consecutive p...

journal_title：Clinical cardiology

authors： Zhao JL,Yang YJ,Zhang YH,Pei WD,Sun YH,Chen JL,Gao RL

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:The implantable cardioverter defibrillator (ICD) is the most effective treatment available for terminating potentially life-threatening ventricular tachycardia and ventricular fibrillation and reducing the risk of mortality. Despite its established health benefits, ICD therapy is accompanied by a unique arra...

journal_title：Clinical cardiology

authors： Stutts LA,Cross NJ,Conti JB,Sears SF

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The frequency of acute myocardial infarction (AMI) peaks on Mondays and in the mornings. However, the distribution of the types of acute coronary syndromes (ACS), including unstable angina (UA), has not been systematically evaluated. HYPOTHESIS:The distribution of the types of ACS and clinical presentations...

journal_title：Clinical cardiology

authors： LaBounty T,Eagle KA,Manfredini R,Fang J,Tsai T,Smith D,Rubenfire M

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Little is known about the relationship of body fluid status with the levels and fluctuations of B-type natriuretic peptide (BNP) over the long-term. HYPOTHESIS:If BNP is to become useful for monitoring of patients with chronic heart failure (HF), the levels should reliably reflect both decompensation and im...

journal_title：Clinical cardiology

authors： Kataoka H

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Chronic stress is estimated to increase the risk of cardiovascular (CV) events two-fold. Although stress reduction has been linked to a reduction in CV events, little is known regarding its exact mechanism of benefit. HYPOTHESIS:Yoga and meditation will improve parameters of endothelial function. METHODS:W...

journal_title：Clinical cardiology

authors： Sivasankaran S,Pollard-Quintner S,Sachdeva R,Pugeda J,Hoq SM,Zarich SW

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:In addition to the well-investigated proinflammatory cytokine expression, there is an ever increasing interest in the field of anti-inflammatory response to cardiopulmonary bypass (CPB). Evidence suggests that myocardium serves as an important source of cytokines during reperfusion and application of CPB. Th...

journal_title：Clinical cardiology

authors： Gasz B,Lenard L,Racz B,Benko L,Borsiczky B,Cserepes B,Gal J,Jancso G,Lantos J,Ghosh S,Szabados S,Papp L,Alotti N,Roth E

更新日期：2006-07-01 00:00:00

abstract：:This review examines the issue of preoperative cardiac evaluation from a critical point of view, based on recent medical literature. We reviewed the history of that field and focused on the American College of Cardiology and American Heart Association guidelines, which are a cornerstone in the field of cardiac patient...

journal_title：Clinical cardiology

authors： Barak M,Ben-Abraham R,Katz Y

更新日期：2006-05-01 00:00:00

abstract：:The AFFIRM study showed no clear survival advantage for a rhythm versus rate control strategy in patients with atrial fibrillation (AF). However, rhythm control with antiarrhythmic drugs (AADs) is appropriate in a large number of patients with AF. The American College of Cardiology/ American Heart Association/European...

journal_title：Clinical cardiology

authors： Reiffel JA,Naccarelli GV

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Echocardiographic evidence of diastolic dysfunction has been demonstrated during acute cigarette smoking in patients with coronary artery disease. Similar studies in healthy patients have shown conflicting results. Furthermore, it is unclear whether nicotine or some other cigarette-related substance is respo...

journal_title：Clinical cardiology

authors： Gembala MI,Ghanem F,Mann CA,Sorrell VL

更新日期：2006-02-01 00:00:00

abstract：:Left ventricular systolic dysfunction (LVSD) and clinical heart failure are common complications of acute myocardial infarction (AMI) and result in substantially increased mortality and morbidity. Evidence-based cardiovascular protective therapies, including angiotensin-converting enzyme inhibitors, beta blockers, ant...

journal_title：Clinical cardiology

authors： Fonarow GC

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Previously, perfusion defect in the left ventricle was detected by thallium-201 (201T1) single-photon emission computed tomography (SPECT) in aortic regurgitation (AR). The significance of 201T1 SPECT, however, has not been clarified. Limited information is available regarding the relationship between functi...

journal_title：Clinical cardiology

authors： Yasuda H,Taniguchi K,Takahashi T,Sawa Y,Matuda H

更新日期：2005-12-01 00:00:00

abstract：:The pharmacologic management of the patient post myocardial infarction (MI) aims to achieve several goals. Chief among these is to prevent subsequent events, which include death, reinfarction, and rehospitalization. Secondary goals include preventing arrhythmias, minimizing left ventricular (LV) remodeling, and preven...

journal_title：Clinical cardiology

authors： Reiffel JA,American Heart Association.,American College of Cardiology.

更新日期：2005-11-01 00:00:00

abstract：:Sinus tachycardia is the most common rhythm disturbance encountered in clinical practice. Primary sinus tachycardia without an underlying secondary cause, despite often being associated with troublesome symptoms, is often neglected leading to multiple consultations and frustration on part of both the practitioner and ...

journal_title：Clinical cardiology

authors： Yusuf S,Camm AJ

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:There are no studies in the literature related to the effect of beta blockers (BB) on changes in C-reactive protein (CRP) levels after percutaneous coronary intervention (PCI). HYPOTHESIS:We designed a prospective randomized study to investigate the impact of BB therapy on CRP in patients who underwent elec...

journal_title：Clinical cardiology

authors： Atar I,Gülmez O,Atar A,Bozbas H,Yildirir A,Ozin B,Korkmaz ME,Müderrisoglu H

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Acute coronary syndromes (ACS) are characterized by activation of systemic and local inflammatory mediators. The interrelation between these soluble inflammatory markers and their association with markers of myocardial necrosis have not been extensively studied. HYPOTHESIS:The study was undertaken to evalua...

journal_title：Clinical cardiology

authors： Manginas A,Bei E,Chaidaroglou A,Degiannis D,Koniavitou K,Voudris V,Pavlides G,Panagiotakos D,Cokkinos DV

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:The Reduction in ENdpoints with the Angiotensin Antagonist Losartan (RENAAL) study reported that losartan delayed the progression of renal disease in patients with type 2 diabetes and nephropathy. Diabetic or renally impaired patients are at high cardiovascular risk, a risk potentially increased in patients ...

journal_title：Clinical cardiology

authors： Kowey PR,Dickson TZ,Zhang Z,Shahinfar S,Brenner BM,RENAAL Investigators.

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:Females with Ullrich-Turner syndrome (UTS) have typical clinical features such as short stature, ovarian failure, visible dysmorphic stigmata, and abnormalities in different organs such as kidney or heart. HYPOTHESIS:The aim of the present study was to analyze the distribution, prevalence, and relative risk...

journal_title：Clinical cardiology

authors： Völkl TM,Degenhardt K,Koch A,Simm D,Dörr HG,Singer H

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Monocyte chemoattractant protein-1 (MCP-1) participates in the recruitment of mononuclear cells to the vessel wall. HYPOTHESIS:The aim of the study was to evaluate the potential association between serum concentration of MCP-1 and risk of future cardiovascular events in patients with chronic coronary heart ...

journal_title：Clinical cardiology

authors： Haim M,Tanne D,Boyko V,Reshef T,Goldbourt U,Battler A,Mekori YA,Behar S

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Myocardial blush grade (MBG), corrected TIMI frame count (cTFC), and ST-segment reduction are indices of myocardial reperfusion. HYPOTHESIS:We evaluated their predictive value for left ventricular (LV) function recovery by gated single-photon emission computed tomography (SPECT) after acute myocardial infar...

journal_title：Clinical cardiology

authors： Bellandi F,Leoncini M,Maioli M,Toso A,Gallopin M,Piero Dabizzi R

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:The Senning operation for transposition of the great arteries (TGA) was first introduced by Senning in 1959 and was revived by Quaegebeur et al. in the late 1970s, thus becoming the intervention of choice for the correction of TGA in many centers. HYPOTHESIS:The purpose of this study was to evaluate the lon...

journal_title：Clinical cardiology

authors： Agnetti A,Carano N,Cavalli C,Tchana B,Bini M,Squarcia U,Frigiola A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Despite a high prevalence of hypertension in the population with CAD, there are limited data describing the clinical characteristics and treatments, as well as their interrelations in these patients. This is particularly true for black and Hispanic patients who have been underrepresented in randomized CAD tr...

journal_title：Clinical cardiology

authors： Cooper-DeHoff RM,Handberg EM,Cohen J,Kowey P,Messerli FH,Mancia G,Cangiano JL,Gaxiola E,Garcia-Barreto D,Hewkin AC,Pepine CJ,INVEST Investigators.

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The finding of aortic regurgitation at a classical examination is a diastolic murmur. HYPOTHESIS:Aortic regurgitation is more likely to be associated with a systolic than with a diastolic murmur during routine screening by a noncardiologist physician. METHODS:In all, 243 asymptomatic patients (mean age 42 ...

journal_title：Clinical cardiology

authors： Heidenreich PA,Schnittger I,Hancock SL,Atwood JE

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Exercise-induced dyspnea is a frequent feature in patients with hyperthyroidism. HYPOTHESIS:Data from clinical studies to elucidate the origin of this symptom are lacking. In the current study, we examined the hemodynamic and oxygenation responses to exercise and beta-adrenergic blockade in patients with hy...

journal_title：Clinical cardiology

authors： Monachini MC,Lage SG,Ran MA,Cardoso RH,Medeiros C,Caramelli B,Sposito AC,Ramires JA

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Although the outcome of patients with angiographically insignificantly narrowed coronary arteries (INCA) is not clearly defined, such lesions can progress or rupture, thus causing cardiovascular morbidity. Preventive therapy with aspirin and lipid-lowering drugs therefore seems warranted in these patients. ...

journal_title：Clinical cardiology

authors： Henkin Y,Abuful A,Yosefi C,Elis A,Ilia R,Gidron Y

更新日期：2004-06-01 00:00:00